Preoperative Antibiotic Dosing for Total Knee Arthroplasty

Intraosseous administration of prophylactic antibiotics

Cefazolin 1 gram will be given through an intraosseous cannula, placed into the medial aspect of the proximal tibia, after draping and before skin incision. The cefazolin will be administered as a bolus in 200 mL of normal saline.