NCT02427932View on ClinicalTrials.gov

Pharmacokinetic (PK) and Pharmacodynamic (PD) Modeling of Ampicillin and Gentamicin in Peripartum Patients

CompletedOBSERVATIONAL
Enrollment

45

Participants

Timeline

Start Date

May 31, 2015

Primary Completion Date

January 31, 2017

Study Completion Date

January 31, 2017

Conditions
Drug Metabolism During Pregnancy
Interventions
DRUG

Ampicillin

Pregnant participants will receive Ampicillin 2g IV loading dose followed by 1g IV every 4 hrs until delivery for Group B Strep prophylaxis; non-pregnant participants will receive Ampicillin for qualifying diagnosis

DRUG

Ampicillin and Gentamicin

Pregnant participants will receive Ampicillin 2g IV every 6hrs along with Gentamicin 5mg/kg IV every 24 hrs for chorioamnionitis; non-pregnant participants will receive for qualifying diagnosis

DRUG

Gentamicin

Prescribed to non-pregnant participants

Trial Locations (1)

94304

Lucille Packard Children's Hospital, Palo Alto

All Listed Sponsors
collaborator

David Drover, MD

UNKNOWN

lead

Stanford University

OTHER

NCT02427932 - Pharmacokinetic (PK) and Pharmacodynamic (PD) Modeling of Ampicillin and Gentamicin in Peripartum Patients | Biotech Hunter | Biotech Hunter