CBT Plus SMC Compared to SMC for Persistent Physical Symptoms in Secondary Care (PRINCE)

NACompletedINTERVENTIONAL
Enrollment

324

Participants

Timeline

Start Date

July 31, 2015

Primary Completion Date

January 31, 2019

Study Completion Date

January 31, 2019

Conditions
Persistent Physical Symptoms (PPS)
Interventions
BEHAVIORAL

Cognitive behavioural therapy (CBT)

Behavioral: Cognitive behavioural therapy (CBT) The CBT intervention used in the trial has been adapted for people with PPS and it is based on a model of understanding PPS (Deary et al 2007). The therapy aims to help the patient develop an understanding of the relationship between cognitive, physiological and behavioural aspects of their problem; to understand factors that may be maintaining the problem and to learn how to modify their behavioural and cognitive responses in order to improve quality of life. The approach is transdiagnostic in that it targets processes and underlying mechanisms that affect disorders similarly, rather than focusing on how they are diagnostically different. The approach is personalised during therapy following a detailed assessment.

Trial Locations (7)

Unknown

Guy's Hospital, London

King's College Hospital, London

Queen Elizabeth Hospital, London

Royal Free Hospital, London

St Thomas' Hospital, London

University Hospital Lewisham, London

Princess Royal University Hospital, Orpington

All Listed Sponsors
collaborator

South London and Maudsley NHS Foundation Trust

OTHER

lead

King's College London

OTHER

NCT02426788 - CBT Plus SMC Compared to SMC for Persistent Physical Symptoms in Secondary Care (PRINCE) | Biotech Hunter | Biotech Hunter