22
Participants
Start Date
September 30, 2015
Primary Completion Date
March 31, 2017
Study Completion Date
March 31, 2017
Active repetitive Transcranial Magnetic Stimulation (rTMS)
The treatments will be administered daily (five days/week) for two weeks, followed by three days on the third week (total of 13 treatments). Patients of both real and sham treatment groups will undergo rTMS treatment of 1.5-second duration trains of pulses at 20 Hz for a total of 25 trains with intertrain interval of 10 seconds applied to DLPFC bilaterally at 100% of the resting motor threshold. Thus, there will be a total of 1500 pulses per two sides of the brain per day, which is well within the safety limit of the rTMS application. During the intertrain intervals, the patients will be presented a series of objects and actions and asking to name them. The images will be projected on the wall in front of patient with duration of three seconds for each image. The aim is to keep the brain active while we stimulate it with rTMS.
Sham repetitive Transcranial Magnetic Stimulation (rTMS)
Sham rTMS is similar to Active rTMS but instead of a real coil, it uses a coil that attenuates the pulses such that no current will be induced in the brain.
Riverview Health Center, Winnipeg
University of Manitoba
OTHER