Reducing Micro Vascular Dysfunction in Acute Myocardial Infarction by Ticagrelor

PHASE4UnknownINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

May 31, 2015

Primary Completion Date

October 31, 2017

Study Completion Date

October 31, 2019

Conditions
Myocardial Infarction
Interventions
DRUG

Ticagrelor

After a standard loading dose of 180 mg ticagrelor in the ambulance (before primary PCI), patients will receive a maintenance dose of ticagrelor 90 mg twice a day for 1 year.

DRUG

Prasugrel

After a standard loading dose of 180 mg ticagrelor in the ambulance (before primary PCI), patients will receive a single loading dose of prasugrel 60 mg (1 day after standard loading dose ticagrelor),followed by a maintenance dose of prasugrel 10 mg once a day for 1 year.

Trial Locations (1)

1081 HV

VU University Medical Center, Amsterdam

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Erasmus Medical Center

OTHER

collaborator

Hospital San Carlos, Madrid

OTHER

collaborator

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER

collaborator

University Medical Center Nijmegen

OTHER

lead

Amsterdam UMC, location VUmc

OTHER