Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma

PHASE1CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

October 5, 2015

Primary Completion Date

March 28, 2025

Study Completion Date

March 28, 2025

Conditions
Diffuse Intrinsic Pontine Glioma
Interventions
RADIATION

Radiation Therapy

Undergo radiation therapy

DRUG

Temsirolimus

Given IV

DRUG

Vorinostat

Given PO

Trial Locations (1)

77030

M D Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

M.D. Anderson Cancer Center

OTHER

NCT02420613 - Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma | Biotech Hunter | Biotech Hunter