Reverse Prediction of Ion Channel Remodeling in Patients With Atrial Fibrillation Utilizing Monophasic Action Potential and Mathematical Modeling

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

August 28, 2015

Primary Completion Date

March 2, 2017

Study Completion Date

March 2, 2017

Conditions
Atrial Fibrillation
Interventions
DEVICE

Monophasic action potential(MAP) catheter

After ordinary procedure for electrophysiologic study or catheter ablation, the investigators will replace conventional catheter to monophasic action potential (MAP) recording catheter through right femoral sheath. MAP recording catheter is introduced to endocardial surface of atrium, and we record atrial MAP at variable pacing cycle lengths: steady state cycle lengths of 600, 400, 300, 240, 220, 240, 260, 300, 400 and 600 ms. At each cycle length, pacing was applied for 20 sec. It takes less than 5 min to acquire MAP recordings.

Trial Locations (1)

120-752

Severance Cardiovascular Hospital, Yonsei University Health System, Seoul

All Listed Sponsors
lead

Yonsei University

OTHER

NCT02414815 - Reverse Prediction of Ion Channel Remodeling in Patients With Atrial Fibrillation Utilizing Monophasic Action Potential and Mathematical Modeling | Biotech Hunter | Biotech Hunter