2,516
Participants
Start Date
January 25, 2016
Primary Completion Date
July 31, 2020
Study Completion Date
May 31, 2021
rifapentine
Regimen 2: Rifapentine is substituted for rifampin as the basis of 4-month treatment
rifapentine and moxifloxacin
Regimen 3: In addition to the single substitution described for regimen 2, a second substitution is added, of moxifloxacin for ethambutol.
control
standard six-month treatment
TBTC Site 41/ ACTG Site 30313 Parirenyatwa Clinical Research Site, Harare
TBTC Site 34 Wits Health Consortium Perinatal HIV Research Unit (PHRU), Soweto
TBTC Site 49/ ACTG Site 12301 Soweto ACTG CRS, Soweto
TBTC Site 07/ ACTG Site 11101 Wits Helen Joseph CRS, Johannesburg
TBTC Site 06/ ACTG Site 11201 Durban International Clinical Research Site, Durban
TBTC Site 01/ACTG Site 8950 FAM CRU, Parow Valley
TBTC Site 10/ ACTG Site 31718 TASK Applied Science, Bellville
TBTC Site 09/ ACTG Site 31792 University of Cape Town Lung Institute (Pty) Ltd, Mowbray
TBTC Site 08/ ACTG Site 31793 South African Tuberculosis Vaccine Initiative (SATVI), Cape Town
TBTC Site 37 Vietnam NTP/UCSF Research Collaboration, Hanoi
TBTC Site 24 Columbia Unversity, New York
TBTC Site 42/ ACTG Site 31802 The Thai Red Cross AIDS Research Centre, Pathumwan
TBTC Site 02/ ACTG 12501 Kenya Medical Research Institute/Walter Reed Project Clinical Research Center (KEMRI/WRP) CRS, Kericho
TBTC Site 03/ ACTG Site 12601 Moi University Clinical Research Site, Eldoret
TBTC Site 39/ ACTG Site 31460 Kisumu CRS, Kisumu
TBTC Site 69/ ACTG Site 31784 Thai-CTIU, CMU HIV Treatment CRS, Muang Chiang Mai
TBTC Site 20 UNTHSC (University of North Texas Health Science Center), Fort Worth
TBTC Site 62 Baylor College of Medicine & Affiliated Hospitals/VA, Houston
TBTC Site 82/ ACTG Site 801 USCF AIDS CRS, San Francisco
TBTC Site 44/ ACTG Site 11701 CART CRS, YRGCARE Medical Centre VHS, Chennai
TBTC Site 43/ ACTG Site 31441 BJ Medical College, Pune
TBTC Site 63 San Antonio VA Medical Center (South Texas Group), San Antonio
TBTC Site 94/ ACTG Site 12201 Hospital Nossa Senhora da Conceicao, Porto Alegre
TBTC Site 91/ ACTG Site 12101 Insituto Nacional de Pesquisa Clínica Evandro Chagas, Rio de Janeiro
TBTC Site 36 TB and Chest Service of Hong Kong, China, Hong Kong
TBTC Site 04/ ACTG Site 30301 Blantyre CRS (or College of Medicine - Johns Hopkins Research Project, COM-JHP), Blantyre
TBTC Site 05/ ACTG Site 12001 UNC Project Tidziwe Centre, Lilongwe
TBTC Site 11/ ACTG Site 12401 Joint Clinical Research Centre, Kampala Clinical Research Site, Kampala
TBTC Site 30 Uganda-Case Western Reserve Research Collaboration, Kampala
TBTC Site 67/ ACTG Site 31730 GHESKIO centers IMIS, Port-au-Prince
TBTC Site 45/ ACTG Site 30022: Les Centres Gheskio (INLR), Port-au-Prince
TBTC Site 90/ ACTG Site 11301 Asociacion Civil Impacta Salud y Educacion, Lima
TBTC Site 93/ ACTG Site 11302 CRS San Miguel, Lima
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NETWORK
Centers for Disease Control and Prevention
FED