Bronchial Inflammation and Hyperresponsiveness After Oil Supplementation

NACompletedINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

April 30, 2015

Primary Completion Date

February 29, 2016

Study Completion Date

July 31, 2016

Conditions
Exercise-induced Asthma
Interventions
OTHER

Exercise challenge in a cold chamber

Exercise challenge is defined as running on a treadmill for 6-8 minutes on submaximal work load in a cold chamber.

OTHER

Methacholine challenge

Nebulized metacholine administered at following doses: 0,01mg, 0,1mg, 0,4mg, 0,8mg und 1,6mg

DIETARY_SUPPLEMENT

Oil supplementation verum

Patients and subjects will take double blind an oil supplementation with middle-chain and polyunsaturated fatty acids for four weeks

DIETARY_SUPPLEMENT

Oil supplementation placebo

Patients and subjects will take double blind sunflower oil for four weeks

Trial Locations (1)

60590

Goethe University Hospital Frankfurt, Frankfurt am Main

All Listed Sponsors
lead

Johann Wolfgang Goethe University Hospital

OTHER

NCT02410096 - Bronchial Inflammation and Hyperresponsiveness After Oil Supplementation | Biotech Hunter | Biotech Hunter