POSNOC - A Trial Looking at Axillary Treatment in Early Breast Cancer

NAActive, not recruitingINTERVENTIONAL
Enrollment

1,900

Participants

Timeline

Start Date

August 1, 2014

Primary Completion Date

July 31, 2026

Study Completion Date

December 31, 2026

Conditions
Breast Cancer
Interventions
OTHER

Adjuvant therapy

Adjuvant therapy will include chemotherapy and/or endocrine therapy for all women, and radiotherapy to breast or chest wall if indicated. Human epidermal growth factor receptor 2 (HER2) targeted treatment may also be administered when indicated.

PROCEDURE

Axillary treatment

Axillary treatment can be axillary node clearance or axillary radiotherapy as per local guidelines.

Trial Locations (50)

Unknown

Royal Adelaide Hospital, Adelaide

Bankstown-Lidcocombe Hospital, Bankstown

Maeter Hospital, Brisbane

Coffs Harbour Health Campus, Coffs Harbour

Monash Cancer Centre, Melbourne

Royal Melbourne and Royal Women's Hospital, Melbourne

Sir Charles Gairdner Hospital, Perth

Riverina Cancer Care Centre, Wagga Wagga

Waikato Hospital, Hamilton

Rotorua Hospital, Rotorua

Ashford and St Peter's Hospitals NHS Foundation Trust, Ashford

Barnsley Hospital, Barnsley

Belfast City Hospital, Belfast

City Hospital, Birmingham

Queen Elizabeth Hospital, Birmingham

Royal Bolton Hospital, Bolton

Bradford Royal Infirmary, Bradford

Princess of Wales Hospital, Bridgend

Addenbrooke's Hospital, Cambridge

University Hospital Llandough, Cardiff

Darrent Valley Hospital, Dartford

Royal Derby Hospital, Derby

Eastbourne District General Hospital, Eastbourne

Western General Hospital, Edinburgh

Medway Maritime Hospital, Gillingham

Western Infirmary, Glasgow

Inverclyde Royal Hospital, Greenock

Harrogate District Hospital, Harrogate

University Hospital Crosshouse, Kilmarnock

Forth Valley Hospital, Larbert

St James's University Hospital, Leeds

University Hospitals of Leicester NHS Trust, Leicester

Guy's and St Thomas' NHS Foundation Trust, London

Royal Marsden Hospital, London

Luton and Dunstable University Hospital, Luton

Macclesfield District General Hospital, Macclesfield

Maidstone Hospital, Maidstone

North Manchester General Hospital, Manchester

Wythenshawe Hospital, Manchester

Royal Victoria Infirmary, Newcastle upon Tyne

Royal Gwent Hospital, Newport

The Norfolk and Norwich University Hospital, Norwich

Oxford University Hospitals, Oxford

Peterborough City Hospital, Peterborough

Derriford Hospital, Plymouth

Rotherham General Hospital, Rotherham

Royal Stoke University Hospital, Stoke-on-Trent

Royal Cornwall Hospital, Truro

Wishaw General Hospital, Wishaw

New Cross Hospital, Wolverhampton

All Listed Sponsors
collaborator

University of Nottingham

OTHER

collaborator

Sussex Health Outcomes Research & Education in Cancer (SHORE-C)

UNKNOWN

collaborator

NCRI Radiotherapy Trials QA Group (RTTQA)

UNKNOWN

collaborator

Breast Cancer Trials, Australia and New Zealand

OTHER

lead

University Hospitals of Derby and Burton NHS Foundation Trust

OTHER

NCT02401685 - POSNOC - A Trial Looking at Axillary Treatment in Early Breast Cancer | Biotech Hunter | Biotech Hunter