Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin

PHASE1CompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 31, 2015

Primary Completion Date

August 31, 2015

Study Completion Date

September 30, 2015

Conditions
Cocaine Abuse
Interventions
DRUG

Lorcaserin

10 mg 2 times per day from Day 3 to 9 and one time on Day 10

DRUG

Placebo

10 mg 2 times per day from Day 3 to 9 and one time on Day 10

DRUG

Cocaine Infusion

Screening / Session 1, Study Day -2: 20 mg cocaine, followed by a saline infusion, followed by 40 mg cocaine Baseline/ Session 2, Study Day 1: Saline or 20 mg cocaine followed by either 20 mg cocaine or saline Baseline / Session 3, Study Day 2: Saline or 40 mg cocaine followed by either 40 mg cocaine or saline Treatment / Session 4, Study Day 9: Saline or 20 mg cocaine followed by either 20 mg cocaine or saline Treatment / Session 5, Study Day10: Saline or 40 mg cocaine followed by either 40 mg cocaine or saline

Trial Locations (1)

66212

Vince Associates Clinical Research, Inc., Overland Park

All Listed Sponsors
lead

National Institute on Drug Abuse (NIDA)

NIH

NCT02393599 - Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin | Biotech Hunter | Biotech Hunter