16
Participants
Start Date
February 5, 2016
Primary Completion Date
January 21, 2019
Study Completion Date
February 18, 2019
Anakinra
The dose of Anakinra will be 2mg/kg (patients \<10kg and/or \<8 months: 4mg/kg). If the patient remains febrile (fever \>38°C), he will receive a double dose of anakinra 4mg/kg (patients \<10kg and/or \<8 months: 6mg/kg) at day1 instead of 2mg/kg. If the patient does not respond to the 4mg/kg dose at visit 3; d1 within 24 hours, he will receive at visit 4; d2, 6mg/kg of anakinra (patients \<10kg and/or \<8 months: 8mg/kg). Treatment will be continued until they have achieved complete response as defined in the outcome measurement section, and during a maximum of 15 days.
AP-HP,Bicêtre Hospital, Le Kremlin-Bicêtre
Collaborators (1)
Swedish Orphan Biovitrum
INDUSTRY
Assistance Publique - Hôpitaux de Paris
OTHER