Randomized Trial Comparing Rituximab Against Mycophenolate Mofetil in Children Wtih Refractory Nephrotic Syndrome

PHASE3TerminatedINTERVENTIONAL
Enrollment

3

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

December 7, 2016

Study Completion Date

January 18, 2017

Conditions
Frequent Relapsing Nephrotic SyndromeSteroid Dependent Nephrotic Syndrome
Interventions
DRUG

Rituximab

We hypothesize that the anti-CD20 monoclonal antibody Rituximab will be more effective in maintaining remission in children who have already had one relapse while receiving MMF

DRUG

MMF

Subjects randomized to MMF, will continue MMF as scheduled by the investigator

Trial Locations (1)

43205

Nationwide Children's Hospital, Columbus

All Listed Sponsors
collaborator

Emory University

OTHER

collaborator

Children's Healthcare of Atlanta

OTHER

collaborator

Genentech, Inc.

INDUSTRY

collaborator

The NephCure Foundation

OTHER

lead

Nationwide Children's Hospital

OTHER