Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma

PHASE3CompletedINTERVENTIONAL
Enrollment

906

Participants

Timeline

Start Date

March 16, 2015

Primary Completion Date

November 26, 2018

Study Completion Date

October 16, 2024

Conditions
Melanoma
Interventions
DRUG

Ipilimumab

Specified dose on specified days

DRUG

Nivolumab

Specified dose on specified days

OTHER

Placebo matching Ipilimumab

Specified dose on specified days

OTHER

Placebo matching Nivolumab

Specified dose on specified days

Trial Locations (136)

0

Local Institution - 0166, Dublin

4

Local Institution - 0108, Dublin

333

Local Institution - 0130, Taoyuan District

404

Local Institution - 0132, Taichung

833

Local Institution - 0131, Kaohsiung City

1090

Local Institution - 0038, Brussels

1122

Local Institution - 0163, Budapest

1200

Local Institution - 0040, Brussels

1426

Local Institution - 0142, Capital Federal

2050

Local Institution - 0081, Camperdown

2065

Local Institution - 0078, Wollstonecraft

2145

Local Institution - 0080, Westmead

2196

Local Institution - 0148, Johannesburg

Local Institution - 0147, Saxonwold, Johannesburg

2290

Local Institution - 0079, Gateshead

3000

Local Institution - 0039, Leuven

3084

Local Institution - 0075, Heidelberg

3100

Local Institution - 0109, Oslo

3181

Local Institution - 0077, Prahran

4000

Local Institution - 0140, San Miguel de Tucumán

4120

Local Institution - 0082, Greenslopes

4215

Local Institution - 0083, Southport

5000

Local Institution, Córdoba

Local Institution - 0084, Adelaide

5020

Local Institution - 0168, Salzburg

5021

Local Institution - 0098, Bergen

6009

Local Institution - 0085, Nedlands

7570

Local Institution - 0146, Kraaifontein

7700

Local Institution - 0181, Cape Town

8036

Local Institution - 0169, Graz

8091

Local Institution - 0167, Zurich

9000

Local Institution - 0037, Ghent

10016

Local Institution - 0024, New York

10065

Local Institution - 0033, New York

11526

Local Institution - 0086, Athens

13385

Local Institution - 0135, Marseille

16128

Local Institution - 0116, Genova

18015

Local Institution - 0001, Bethlehem

18103

Local Institution - 0022, Allentown

18547

Local Institution - 0087, Neo Faliro

20007

Local Institution - 0004, Washington D.C.

20133

Local Institution - 0113, Milan

22908

Local Institution - 0027, Charlottesville

24127

Local Institution - 0112, Bergamo

27710

Local Institution - 0025, Durham

28007

Local Institution - 0119, Madrid

28204

Local Institution - 0003, Charlotte

29425

Local Institution - 0026, Charleston

30322

Local Institution - 0016, Atlanta

31059

Local Institution - 0137, Toulouse

32207

Local Institution - 0012, Jacksonville

32806

Local Institution - 0030, Orlando

33140

Local Institution - 0019, Miami Beach

33521

Local Institution - 0048, Tampere

33612

Local Institution - 0032, Tampa

41009

Local Institution - 0121, Seville

43210

Local Institution - 0157, Columbus

44000

Local Institution - 0134, Nantes

46014

Local Institution - 0122, Valencia

47014

Local Institution - 0115, Meldola (FC)

53100

Local Institution - 0110, Siena

55407

Local Institution - 0002, Robbinsdale

59037

Local Institution - 0138, Lille

60637

Local Institution - 0106, Chicago

63110

Local Institution - 0017, St Louis

69495

Local Institution - 0133, Pierre-Bénite

72205

Local Institution - 0036, Little Rock

75010

Local Institution - 0136, Paris

75246

Local Institution - 0005, Dallas

80045

Local Institution - 0010, Aurora

80131

Local Institution - 0107, Napoli

90025

Local Institution - 0189, Los Angeles

94109

Local Institution - 0021, San Francisco

94143

Local Institution - 0006, San Francisco

97213

Local Institution - 0031, Portland

97239

Local Institution - 0029, Portland

98109

Local Institution - 0126, Seattle

200542

Local Institution - 0156, Craiova

400015

Local Institution - 0153, Romania

1040045

Local Institution - 0158, Chuo-ku

3058576

Local Institution - 0174, Tsukuba

3908621

Local Institution - 0160, Matsumoto

4093898

Local Institution - 0180, Chuo-shi

4118777

Local Institution - 0159, Sunto-gun

5400006

Local Institution - 0176, Osaka

8128582

Local Institution - 0161, Fukuoka

8608556

Local Institution - 0162, Kumamoto

9518566

Local Institution - 0175, Niigata

92093-0698

Local Institution - 0117, La Jolla

02215

Local Institution - 0013, Boston

Local Institution - 0170, Boston

Local Institution - 0171, Boston

48109-5869

Local Institution - 0015, Ann Arbor

07601

Local Institution - 0123, Hackensack

08903

Local Institution - 0095, New Brunswick

37203-1624

Local Institution - 0014, Nashville

T6G 1Z2

Local Institution - 0051, Edmonton

V5Z 4E6

Local Institution - 0074, Vancouver

M5G 2M9

Local Institution - 0094, Toronto

H3T 1E2

Local Institution - 0105, Montreal

G1J 1Z4

Local Institution - 0046, Québec

500 05

Local Institution - 0101, Hradec Králové

708 52

Local Institution - 0102, Ostrava-Poruba

110 00

Local Institution - 0099, Prague

128 08

Local Institution - 0100, Prague

00029

Local Institution - 0047, Helsinki

01

Local Institution - 0063, Dublin

Unknown

Local Institution - 0064, Galway

Padova

Local Institution - 0111, Padua

00144

Local Institution - 0114, Roma

466-8560

Local Institution - 0179, Nagoya

1081 HV

Local Institution - 0042, Amsterdam

9713 GZ

Local Institution - 0045, Groningen

6525GA

Local Institution - 0043, Nijmegen

5504 DB

Local Institution - 0041, Veldhoven

80-219

Local Institution - 0150, Gdansk

31-115

Local Institution - 0149, Krakow

02-781

Local Institution - 0152, Warsaw

0075

Local Institution - 0145, Pretoria

05505

Local Institution - 0144, Songpa-gu

03080

Local Institution - 0129, Seoul

03722

Local Institution - 0127, Seoul

06351

Local Institution - 0128, Seoul

08036

Local Institution - 0120, Barcelona

413 45

Local Institution - 0050, Gothenberg

221 85

Local Institution - 0096, Lund

BS2 8ED

Local Institution - 0057, Bristol

SA2 8QA

Local Institution - 0052, Swansea

SW3 6JJ

Local Institution - 0165, London

M20 4BX

Local Institution - 0054, Manchester

SO16 6YD

Local Institution - 0056, Southampton

HA6 2JR

Local Institution - 0177, Northwood

OX3 7LJ

Local Institution - 0055, Oxford

NE7 7DN

Local Institution - 0060, Newcastle upon Tyne

LE15WW

Local Institution - 0097, Leicester

SM2 5PT

Local Institution - 0053, Surrey

Sponsors
All Listed Sponsors
collaborator

Ono Pharmaceutical Co. Ltd

INDUSTRY

lead

Bristol-Myers Squibb

INDUSTRY