9
Participants
Start Date
July 31, 2015
Primary Completion Date
March 9, 2018
Study Completion Date
March 9, 2018
Prazosin
A starting dose of Prazosin (1mg capsule) will be given at Week # 1 of this arm. Symptoms will be reassessed and medication will be adjusted by 1-2 mg increments every 7 days for 3 weeks based on clinical response and severity of night mares, to achieve maximum therapeutic benefit while monitoring adverse effects using side effects scale on weekly basis (psychiatrist will be using the scale at every visit). The end point for capping the Prazosin dose will be 6 mg daily.
Placebo
Prazosin-matched placebo pill
Prazosin
A starting dose of Prazosin (1mg capsule) will be given at Week # 5 of this arm. Symptoms will be reassessed and medication will be adjusted by 1-2 mg increments every 7 days for 3 weeks based on clinical response and severity of night mares, to achieve maximum therapeutic benefit while monitoring adverse effects using side effects scale on weekly basis (psychiatrist will be using the scale at every visit). The end point for capping the Prazosin dose will be 6 mg daily.
Placebo
Prazosin-matched placebo pill
Penn State College of Medicine, Milton S. Hershey Medical Center, Hershey
Milton S. Hershey Medical Center
OTHER