Treatments Against RA and Effect on FDG-PET/CT

PHASE4CompletedINTERVENTIONAL
Enrollment

159

Participants

Timeline

Start Date

July 31, 2016

Primary Completion Date

May 31, 2021

Study Completion Date

May 31, 2021

Conditions
Arthritis, Rheumatoid
Interventions
DRUG

Methotrexate

Subjects entering trial will continue on MTX dose of at least 15mg MTX/week. At the discretion of the treating rheumatologist, may be switched to SQ route.

DRUG

Sulfasalazine

1 gm bid

DRUG

Hydroxychloroquine

200 mg twice daily, not to exceed 6.5mg/kg

DRUG

Etanercept

50 mg SC weekly

DRUG

Adalimumab

40 mg SQ every other week

Trial Locations (31)

10003

New York University School of Medicine, New York

10029

Mount Sinai- Icahn School of Medicine, New York

10032

Columbia University Medical Center, New York

11021

Northwell Health, Great Neck

15261

University of Pittsburgh Medical Center, Pittsburgh

16635

Altoona Research Center, Duncansville

19104

University of Pennsylvania, Philadelphia

20902

The Center for Rheumatology and Bone Research, Wheaton

27599

University of North Carolina at Chapel Hill, Chapel Hill

33324

IRIS Research and Development, Plantation

33609

Southwest Florida Clinical Research Center, Tampa

33765

Robert W. Levin, MD, PA, Clearwater

35294

University of Alabama at Birmingham, Birmingham

40508

University of Kentucky, Lexington

44195

Cleveland Clinic, Cleveland

48109

University of Michigan, Ann Arbor

63110

Washington University Medical Center, St Louis

75231

Metroplex Clinical Research Center, Dallas

76508

Baylor Scott & White Medical Center- Temple, Temple

77030

University of Texas Health Science Center at Houston, Houston

90095

David Geffen School of Medicine at UCLA, Los Angeles

91307

Nazanin Firooz MD, Inc., West Hills

92260

Desert Medical Advances, Palm Desert

92354

Loma Linda University Clinical Trial Center, Loma Linda

92563

Brigid Freyne, MD Inc., Murrieta

94110

University of California San Francisco, San Francisco

97329

Oregon Health & Science University, Portland

98122

Seattle Rheumatology Associates, Seattle

02114

Massachusetts General Hospital, Boston

02115

Brigham and Women's Hospital, Boston

03756

Dartmouth-Hitchcock Medical Center, Lebanon

All Listed Sponsors
collaborator

Columbia University

OTHER

lead

Brigham and Women's Hospital

OTHER

NCT02374021 - Treatments Against RA and Effect on FDG-PET/CT | Biotech Hunter | Biotech Hunter