NCT02342756 - Esophageal Pressure-Guided Optimal PEEP/mPaw in CMV and HFOV: The EPOCH Study | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 31, 2015

Primary Completion Date

December 31, 2017

Study Completion Date

December 31, 2017

Conditions

Respiratory Distress Syndrome, AdultVentilator-Induced Lung Injury

Interventions

DEVICE

Targeting transpulmonary pressure to avoid VILI

Set different values of PEEP (CMV) and mPaw (HFOV) to obtain determined values of transpulmonary pressure (0 and 15 centimeters of water) and to determine the impact of ventilation on VILI

Trial Locations (2)

M5G 1X5

Intensive Care Unit (ICU) of Mount Sinai Hospital, Toronto

M5G 2C4

Medical Surgical ICU - Toronto General Hospital, Toronto