Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI)

NACompletedINTERVENTIONAL
Enrollment

5,413

Participants

Timeline

Start Date

November 30, 2013

Primary Completion Date

March 31, 2019

Study Completion Date

March 31, 2019

Conditions
STEMIMyocardial Reperfusion Injury
Interventions
DEVICE

Remote ischemic conditioning

An automated autoRIC™ cuff will be placed on the upper arm and inflated to 200mmHg for 5 minutes and then deflated for 5 minutes, a cycle which will be undertaken 4 times in total.

DEVICE

Control

An automated autoRIC™ cuff will be placed on the upper arm and a simulated inflation and deflation protocol will be applied.

Trial Locations (35)

2100

Rigshospitalet, Copenhagen

2750

Prehospital Emergency Medical Service, Region Zealand, Ballerup Municipality

5000

Odense University Hospital, Odense

7100

Prehospital Emergency Medical Service , South Denmark Region, Vejle

8200

Prehospital Emergency Medical Service, Central Denmark Region, Aarhus

9000

Prehospital Emergency Medical Service, North Denmark Region, Aalborg

9100

Aalborg University Hospital, Aalborg

26000

Clinical Centre of Serbia, Belgrade

33011

Hospital Universitario Central de Asturias, Oviedo

Unknown

Royal Sussex County Hospital, Brighton

William Harvey Hospital, Ashford

Basildon University Hospital, Basildon

Birmingham Heartlands Hospital, Birmingham

Blackpool Victoria Hospital, Blackpool

Royal Bournemouth Hospital, Bournemouth

Bristol Royal Infirmary, Bristol

Papworth Hospital, Cambridge

Cumberland Infirmary, Carlisle

Coventry University Hospital, Coventry

Kettering General Hospital, Kettering

Leeds General Infirmary, Leeds

Lincoln County Hospital, Lincoln

Hammersmith Hospital, London

Kings College London Hospital, London

St Bartholomew's Hospital, London

St Thomas Hospital, London

The Royal Free Hospital, London

Manchester Royal Infirmary, Manchester

Norfolk and Norwich University Hospital, Norwich

John Radcliffe Hospital, Oxford

Queen Alexandra Hospital, Portsmouth

Northern General Hospital, Sheffield

Lister Hospital, Stevenage

Royal Stoke University Hospital, Stoke-on-Trent

New Cross Hospital, Wolverhampton

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

British Heart Foundation

OTHER

collaborator

London School of Hygiene and Tropical Medicine

OTHER

collaborator

King's College London

OTHER

collaborator

Oxford University Hospitals NHS Trust

OTHER

collaborator

University of Aarhus

OTHER

collaborator

Rigshospitalet, Denmark

OTHER

collaborator

Aalborg University Hospital

OTHER

collaborator

Odense University Hospital

OTHER

collaborator

Hospital Universitario Central de Asturias

OTHER

collaborator

Clinical Centre of Serbia

OTHER

collaborator

Military Medical Academy, Belgrade, Serbia

OTHER

collaborator

Central Denmark Region

OTHER

collaborator

Region of Southern Denmark

OTHER

collaborator

Prehospital Emergency Medical Service, The North Denmark Region

UNKNOWN

collaborator

Region Zealand

OTHER

collaborator

The Danish Medical Research Council

OTHER

collaborator

Aarhus University Hospital

OTHER

collaborator

North Cumbria University Hospitals NHS Trust

OTHER

collaborator

Barts & The London NHS Trust

OTHER

collaborator

Mid and South Essex NHS Foundation Trust

OTHER

collaborator

Sheffield Teaching Hospitals NHS Foundation Trust

OTHER

collaborator

The Leeds Teaching Hospitals NHS Trust

OTHER

collaborator

Manchester University NHS Foundation Trust

OTHER_GOV

collaborator

Norfolk and Norwich University Hospitals NHS Foundation Trust

OTHER

collaborator

The Royal Wolverhampton Hospitals NHS Trust

OTHER_GOV

collaborator

Royal Free Hospital NHS Foundation Trust

OTHER

collaborator

Guy's and St Thomas' NHS Foundation Trust

OTHER

collaborator

East and North Hertfordshire NHS Trust

OTHER_GOV

collaborator

Portsmouth Hospitals NHS Trust

OTHER_GOV

collaborator

United Lincolnshire Hospitals NHS Trust

OTHER

collaborator

Papworth Hospital NHS Foundation Trust

OTHER_GOV

collaborator

Blackpool Victoria Hospital

OTHER

collaborator

Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust

OTHER_GOV

collaborator

Brighton and Sussex University Hospitals NHS Trust

OTHER

collaborator

University Hospitals Coventry and Warwickshire NHS Trust

OTHER

collaborator

University Hospitals of North Midlands NHS Trust

OTHER

collaborator

Heart of England NHS Trust

OTHER

collaborator

Kettering General Hospital NHS Foundation Trust

OTHER

collaborator

Imperial College Healthcare NHS Trust

OTHER

collaborator

University Hospitals Bristol and Weston NHS Foundation Trust

OTHER

collaborator

East Kent Hospitals University NHS Foundation Trust

OTHER_GOV

lead

University College, London

OTHER

NCT02342522 - Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI) | Biotech Hunter | Biotech Hunter