A Study of Lebrikizumab in Participants With Persistent Moderate to Severe Atopic Dermatitis

PHASE2CompletedINTERVENTIONAL
Enrollment

212

Participants

Timeline

Start Date

May 31, 2015

Primary Completion Date

April 30, 2016

Study Completion Date

April 30, 2016

Conditions
Atopic Dermatitis
Interventions
DRUG

Lebrikizumab

Lebrikizumab will be administered SC as per the schedule specified in the respective arms.

DRUG

Placebo

Placebo matching to lebrikizumab will be administered as per the schedule specified in the respective arms.

DRUG

TCS Cream

TCS cream (triamcenolone acetonide 0.1% or hydrocortisone 2.5% cream) twice daily

Trial Locations (74)

1011

CHUV; Dermatologie, Lausanne

2217

St George Dermatology and Skin Cancer Centre, Kogarah

3000

Inselspital Bern; Dermatologie, Bern

3050

Royal Melbourne Hospital; Dermatology Department, Parkville

3053

Skin & Cancer Foundation, Carlton

6160

Fremantle Dermatology, Fremantle

8091

Universitätsspital Zürich; Dermatologische Klinik, Zurich

10048

National Taiwan University Hospital; Department of Dermatology, Taipei

10075

Sadick Research Group, New York

10117

Charite Mitte; Klinik fur Dermatologie, Berlin

20250

Turku Central University Hospital; Dermatology and allergology, Turku

21079

Hopital du Bocage; Dermatologie, Dijon

23502

Virginia Clinical Research Inc., Norfolk

24105

UKSH Kiel; Klinik für Dermatologie, Venerologie und Allergologie, Kiel

28006

Hospital Universitario La Princesa, Servicio dermatologia, Madrid

28007

HUGregorio Marañón, Servicio de dermatología, Madrid

28034

Hospital Ramon y Cajal; servicio dermatologia, Madrid

28046

Hospital Universitario La Paz; Servicio de dermatologia, Madrid

31008

Clinica Universitaria de Navarra; Servicio de Dermatologia, Pamplona

32174

Ameriderm Research, Ormond Beach

33075

Hopital Saint Andre CHU De Bordeaux; Dermatologie, Bordeaux

33520

Tampere University Hospital; Dermatology and allergology, Tampere

33609

Olympian Clinical Research, Tampa

44093

Hopital Hotel Dieu Et Hme; Clinique Dermatologique, Nantes

46014

Hospital General Universitario de Valencia; servicio de dermatología, Valencia

48084

Somerset Skin Centre, Troy

52242

University of Iowa Healthcare; Dermatology, Iowa City

53127

Universitätsklinik Bonn, Bonn

55131

Universitätsklinikum Mainz, Mainz

60590

Klinik Johann Wolfgang von Goethe Uni; Klinik für Dermatologie, Venerologie und Allergologie, Frankfurt

60611

Northwestern University Feinberg School Of Medicine, Chicago

63110

Washington University; Dermatology, St Louis

69495

Centre Hospitalier Lyon Sud; Dermatologie, Pierre-Bénite

70403

National Cheng-Kung University Hospital; Department of Dermatology, Tainan City

77030

University of Texas Medical School-Houston, Houston

78229

Dermatology Clinical Research Center of San Antonio, San Antonio

80045

University of Colorado; Anschutz Cancer Pavilion, Aurora

83301

Chang Gung Medical Foundation;Kaohsiung Branch; Department of Dermatology, Kaohsiung City

90045

Dermatology Research Associate, Los Angeles

92122

UCSD Division of Dermatology, San Diego

94115

Univ of Calif-San Francisco, San Francisco

02114

Massachusetts General Hospital, Boston

97239-4501

Oregon Health & Science University; Department of Dermatology, Portland

T3A 2N1

Institute for Skin Advancement, Calgary

V3R 6A7

Guildford Dermatology Specialists, Surrey

K9J 5K2

Dr. Melinda Gooderham Medicine Professional Corporation, Peterborough

L4B 1A5

The Centre for Dermatology, Richmond Hill

N2J 1C4

K. Papp Clinical Research Inc., Waterloo

N8W 1E6

XLR8 Medical Research Inc., Windsor

L2K 4L5

Innovaderm Research Inc., Montreal

305 99

Faculty Hospital; Department of Dermatology, Pilsen

100 34

Charles University School of Medicine; Deptartment of Dermatology, Prague

401 13

Masarykova nemocnice o.z; kozni oddeleni, Ústí nad Labem

00029

Helsinki University Central Hospital; Skin & Allergy Hospital, Helsinki

06200

Hopital l Archet 2; Ginestriere, Service de; Dermatologie, Nice

07548

SRH Wald-Klinikum Gera GmbH; Hautkrankheiten und Allergologie, Gera

1100 DD

Academisch Medisch Centrum Universiteit Amsterdam; Dermatology and VU University Medical Center, Amsterdam

9700RB

University Medical Center Groningen; Department of Dermatology, Groningen

3584 CX

UMC Utrecht; Dermatology, Utrecht

80-402

Uniwersyteckie Centeum Kliniczne GUMed; Klinika Dermatologii, Wenerologii i Alergologii, Gdansk

90-265

DERMED Centrum Medyczne; Sp zoo, Lodz

70-322

Laser Clinic, Szczecin

33-100

ALERGO-MED Specjalistyczna Przychodnia Lekarska Sp. z o. o, Tarnów

51-318

dermMedica sp.z o.o., Wroclaw

03080

Seoul National University Hospital, Seoul

03722

Severance Hospital, Yonsei University Health System, Seoul

06973

ChungAng University Hospital, Seoul

08025

Hospital de la Santa Creu i Sant Pau; Servicio de Dermatologia, Barcelona

DY1 2HQ

Russells Hall Hospital, Dudley

SE1 9RT

Guys and St Thomas NHS Foundation Trust, Guys Hospital; Skin Therapy Research Unit, London

NE1 4LP

Newcastle University & The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne

OX3 7LJ

Churchill Hospital, Oxford

BH15 2JB

Poole Hospital, Poole

M6 8HD

Salford Royal NHS Foundation Trust, Salford

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT02340234 - A Study of Lebrikizumab in Participants With Persistent Moderate to Severe Atopic Dermatitis | Biotech Hunter | Biotech Hunter