Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

PHASE3CompletedINTERVENTIONAL

Enrollment

493

Participants

Timeline

Start Date

April 14, 2015

Primary Completion Date

November 1, 2016

Study Completion Date

November 1, 2016

Conditions

Open-Angle GlaucomaOcular Hypertension

Interventions

DRUG

Brinzolamide 10 mg/mL / Brimonidine 2 mg/mL fixed combination eye drops, suspension

DRUG

Brinzolamide 10 mg/mL eye drops, suspension

DRUG

Brimonidine 2 mg/mL eye drops, solution

DRUG

Vehicle

Inactive ingredients used as a placebo for masking purposes