Dual Trigger Versus GnRHa Trigger Combined With Luteal HCG Administration

PHASE4RecruitingINTERVENTIONAL
Enrollment

225

Participants

Timeline

Start Date

June 6, 2016

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Infertility
Interventions
DRUG

GnRHa and HCG

Final oocyte maturation will be triggered by dual administration of 0.2 mg of GnRHa preparation (Triptorelin) SC and 1500 IU of HCG preparation IM

DRUG

GnRHa then HCG (single low-dose)

Final oocyte maturation will be triggered by administration of 0.2 mg Triptorelin SC then a single IM bolus of 1500 IU HCG will be administered 35-37 hours after GnRHa trigger (1 hour after oocyte retrieval)

DRUG

GnRHa then HCG (multiple low-doses)

Final oocyte maturation will be triggered by administration of 0.2 mg Triptorelin SC then 3 IM boluses of 500 IU HCG will be administered day 1, day 4 and day 7 after oocyte retrieval

Trial Locations (2)

35111

RECRUITING

Fertility Care Unit (FCU) in Mansoura University Hospital, Al Mansurah

Unknown

RECRUITING

Private fertility care centers, Al Mansurah

All Listed Sponsors
lead

Mansoura University

OTHER