A Safety Study of SGN-CD33A in Combination With Standard-of-care in Patients With AML

PHASE1CompletedINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

December 31, 2014

Primary Completion Date

January 30, 2017

Study Completion Date

April 10, 2018

Conditions
Acute Myeloid LeukemiaAcute Myelogenous Leukemia
Interventions
DRUG

Standard dose cytarabine for induction

100 mg/m2/day Days 1-7

DRUG

SGN-CD33A

Given intravenously Day 1 or Days 1 and 4 of each cycle

DRUG

Daunorubicin

60 mg/m2/day Days 1-3

DRUG

High dose cytarabine for consolidation

3g/m2 on Days 1, 3, and 5 of each cycle

Trial Locations (13)

30384

Sarah Cannon Research Institute, Nashville

35294

University of Alabama at Birmingham, Birmingham

43210

James Cancer Hospital / Ohio State University, Columbus

44195

Cleveland Clinic, The, Cleveland

48201

Karmanos Cancer Institute / Wayne State University, Detroit

60153

Cardinal Bernardin Cancer Center / Loyola University Medical Center, Maywood

75246

Charles A. Sammons Cancer Center / Baylor University Medical Center, Dallas

80218

Colorado Blood Cancer Institute, Denver

91010-3000

City of Hope National Medical Center, Duarte

02114

Massachusetts General Hospital, Boston

07601

Hackensack University Medical Center, Hackensack

77030-4095

MD Anderson Cancer Center / University of Texas, Houston

98109-1024

Fred Hutchinson Cancer Research Center, Seattle

All Listed Sponsors
lead

Seagen Inc.

INDUSTRY

NCT02326584 - A Safety Study of SGN-CD33A in Combination With Standard-of-care in Patients With AML | Biotech Hunter | Biotech Hunter