Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury

NARecruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

October 31, 2014

Primary Completion Date

May 31, 2024

Study Completion Date

May 31, 2024

Conditions
Spinal Cord Injuries
Interventions
OTHER

AIH

Participants will breathe intermittent low oxygen via air generators. The generators will fill reservoir bags attached to a non-rebreathing face mask. Oxygen concentration will be continuously monitored to ensure delivery of fraction of inspired oxygen (FiO2) = 0.10±0.02 (hypoxia). Participants will receive treatment on 5 consecutive days.

OTHER

Walk

30 minutes of walking practice consisting of 5 repetitions of 6-minute walks

OTHER

Strength

30 minutes of isometric ankle plantar flexion torque practice broken into 3 sets of 10 repetitions

Trial Locations (1)

02138

RECRUITING

Spaulding Rehabilitation Hospital, Cambridge

All Listed Sponsors
collaborator

Foundation Wings For Life

OTHER

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

lead

Spaulding Rehabilitation Hospital

OTHER