44
Participants
Start Date
October 31, 2014
Primary Completion Date
May 31, 2024
Study Completion Date
May 31, 2024
AIH
Participants will breathe intermittent low oxygen via air generators. The generators will fill reservoir bags attached to a non-rebreathing face mask. Oxygen concentration will be continuously monitored to ensure delivery of fraction of inspired oxygen (FiO2) = 0.10±0.02 (hypoxia). Participants will receive treatment on 5 consecutive days.
Walk
30 minutes of walking practice consisting of 5 repetitions of 6-minute walks
Strength
30 minutes of isometric ankle plantar flexion torque practice broken into 3 sets of 10 repetitions
RECRUITING
Spaulding Rehabilitation Hospital, Cambridge
Foundation Wings For Life
OTHER
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Spaulding Rehabilitation Hospital
OTHER