21
Participants
Start Date
May 31, 2013
Primary Completion Date
August 31, 2016
Study Completion Date
December 31, 2016
First Treatment Period
(duration: 14 days) Subjects will be randomized to receive either of the 2 interventions (4 grams of solid acetaminophen formulation for two weeks vs. 4 grams of solid acetaminophen formulation + 70 mg/kg/day of liquid propylene glycol)
Washout
(duration: 14 days) At the end of the First intervention period all participants will enter a washout period.
Second Treatment Period
(duration: 14 days) At the end of the washout period, participants will receive the alternative intervention.
Beth Israel Deaconess Medical Center, Boston
Harvard University
OTHER
Beth Israel Deaconess Medical Center
OTHER