Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations

PHASE2CompletedINTERVENTIONAL
Enrollment

57

Participants

Timeline

Start Date

October 31, 2016

Primary Completion Date

July 31, 2019

Study Completion Date

March 31, 2020

Conditions
Tympanic Membrane Perforation
Interventions
DRUG

FGF-2

The FGF-2 method of use comprises a pledget of gelatin foam with human fibroblast growth factor-2 (FGF-2) added to the pledget just before topical application to the tympanic membrane, and the use of Tisseel, a fibrin glue used for applications in ear surgery.

OTHER

Placebo

Placebo comparator using a sterile saline solution.

Trial Locations (2)

78236

Wilford Hall, Lackland Airforce Base, Lackland Air Force Base

02114

Massachusetts Eye and Ear, Boston

All Listed Sponsors
collaborator

United States Department of Defense

FED

lead

Dr. Bradley Welling

OTHER

NCT02307916 - Fibroblast Growth Factor Regeneration of Tympanic Membrane Perforations | Biotech Hunter | Biotech Hunter