Genetic Polymorphisms Associated With CAD

UnknownOBSERVATIONAL
Enrollment

1,173

Participants

Timeline

Start Date

November 30, 2014

Primary Completion Date

November 30, 2017

Study Completion Date

November 30, 2017

Conditions
Coronary Artery Disease
Interventions
GENETIC

IL-1 Genotypes, other SNPs associated with CAD

Genotyping will be carried out by a CLIA-certified genotyping facility at ILI, Waltham MA. DNA concentrations will be adjusted to a range compatible with multiple PCR conditions. Genotyping will be accomplished by performing multiplex polymerase chain reactions (PCR) specifically targeting the surrounding sequences for the SNPs being studied. A single base extension assay will be hybridized to a 48-plex microarray plate and read on a SNPstream Genotyping System (Beckman-Coulter).

Sponsors
All Listed Sponsors
collaborator

University of California, San Diego

OTHER

lead

Interleukin Genetics, Inc.

INDUSTRY