230
Participants
Start Date
July 31, 2015
Primary Completion Date
September 18, 2017
Study Completion Date
March 8, 2018
PRP Injection into Achilles tendon rupture gap
PRP injection delivered into the tendon rupture gap Intervention - PRP Injection: The injection is the intervention. A blood sample is withdrawn from patient. Away from patient part of sample is spun down in centrifuge to produce 'Platelet Rich Plasma' (PRP). Patient returns to treatment area and their own PRP is then injected into tendon rupture gap. This is carried out by a surgeon or extended scope physiotherapist, generally in the outpatient clinic, after a local anaesthetic has been applied. Patient is lying face down during procedure, unaware of treatment given to tendon at back of leg. Remaining blood sample sent for analysis.
Imitation Injection into Achilles tendon rupture gap
Imitation injection delivered into the tendon rupture gap Sham - Imitation Injection: The injection is the intervention. A blood sample is withdrawn from patient. Treatment is prepared. Patient returns to treatment area and a needle (no syringe) is inserted and held into tendon rupture gap to mimic injection (after local anaesthetic has been applied). No active ingredient given. Carried out by surgeon or extended scope physiotherapist, generally in the outpatient clinic. Patient is lying face down during procedure, unaware of treatment given to tendon at back of leg. Blood sample sent for analysis.
John Radcliffe Hospital, Oxford, Oxford
Basildon University Hospital, Basildon
Southmead Hospital, Bristol
University Hospital of Wales, Cardiff
University Hospital Coventry, Coventry
Leighton Hospital, Crewe
Royal Devon & Exeter Hospital, Exeter
Royal Surrey Hospital, Guildford
Aintree Hospital, Liverpool
University Hospital South Manchester, Manchester
Northern General Hospital, Sheffield
Morriston Hospital, Swansea
Leicester Royal Infirmary, Leicester
Royal Liverpool University Hospital, Liverpool
Royal London Hospital, London
Peterborough City Hospital, Peterborough
Musgrove Park Hospital, Taunton
Warrington & Halton Hospitals Trust, Warrington
National Institute for Health Research, United Kingdom
OTHER_GOV
University of Oxford
OTHER