Development of a Novel Stress Testing Protocol to Define the Relationship Between Coronary Microvascular Dysfunction and Diastology in Women With Angina But No Evidence of Obstructive Coronary Artery Disease

Subjects will be asked to squeeze and handgrip dynamometer to increase cardiac metabolic demand

Subjects will breathe a lower concentration of oxygen to simulate the effects of altitude.

Subjects will perform leg exercise to increase metabolic demand.