Study of MEK162 for Children With Low-Grade Gliomas

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

105

Participants

Timeline

Start Date

May 4, 2016

Primary Completion Date

November 2, 2022

Study Completion Date

August 1, 2025

Conditions
Low-Grade GliomasMalignant Neoplasms, BrainSoft Tissue Neoplasms
Interventions
DRUG

MEK162

• MEK162 is currently supplied as film-coated tablets in dose strength of 15 mg. The film-coated tablets consist of MEK162 drug substance, lactose monohydrate, microcrystalline cellulose, colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, and a commercial film coating. The original tablets are yellow to dark yellow capsule-shaped

Trial Locations (15)

10016

New York University, New York

20010

Children's National Heath Systems, Washington D.C.

21287

Johns Hopkins University, Baltimore

30322

Children's Healthcare of Atlanta, Atlanta

33155

Nicklaus Children's Hospital, Miami

35233

Children's Hospital of Alabama, Birmingham

55404

Children's Hospitals and Clinics of Minnesota-Minneapolis, Minneapolis

63110

Washington University School of Medicine, St Louis

75390

University of Texas Southwestern Medical, Dallas

77030

Texas Children's Hospital, Houston

80045

Children's Hospital of Colorado, Aurora

90027

Children's Hospital Los Angeles, Los Angeles

97239

Oregon Health and Science University, Portland

98145

Seattle Children's Hospital, Seattle

02215

Dana Farber Cancer Institute, Boston

All Listed Sponsors
collaborator

Dana-Farber Cancer Institute

OTHER

lead

Children's Hospital Los Angeles

OTHER

NCT02285439 - Study of MEK162 for Children With Low-Grade Gliomas | Biotech Hunter | Biotech Hunter