A Trial of Low-dose Adjunctive alTeplase During prIMary PCI

PHASE2CompletedINTERVENTIONAL
Enrollment

440

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

July 31, 2018

Study Completion Date

May 8, 2019

Conditions
Myocardial Infarction
Interventions
DRUG

Alteplase

Single treatment consisting of a single slow infusion administration after reperfusion with aspiration thrombectomy ± angioplasty but before stenting during primary PCI.

OTHER

Placebo

Single treatment consisting of a single slow infusion administration after reperfusion with aspiration thrombectomy ± angioplasty but before stenting during primary PCI.

Trial Locations (11)

Unknown

Edinburgh Royal Infirmary, Edinburgh

Glenfield Hospital, Leicester

Liverpool Heart and Chest Hospital, Liverpool

James Cook University Hospital, Middlesbrough

G81 4HX

Golden Jubilee National Hospital, Glasgow

LS1 3EX

Leeds General Infirmary, Leeds

EC1A 7BE

Barts Health Centre, St Bartholomew's Hospital, London

M23 9LT

University Hospital of South Manchester NHS Foundation Trust, Manchester

NE7 7DN

Freeman Hospital, Newcastle

SO16 6TD

University Hospital Southampton NHS Foundation Trust, Southampton

WV10 0QP

Heart and Lung Centre, New Cross Hospital, Wolverhampton

All Listed Sponsors
collaborator

University of Glasgow

OTHER

collaborator

National Institute for Health Research, United Kingdom

OTHER_GOV

lead

NHS Greater Glasgow and Clyde

OTHER

NCT02257294 - A Trial of Low-dose Adjunctive alTeplase During prIMary PCI | Biotech Hunter | Biotech Hunter