64
Participants
Start Date
July 31, 2014
Primary Completion Date
May 31, 2018
Study Completion Date
May 31, 2018
Dabigatran etexilate
After inclusion of the patients with LAA thrombus, they are treated according to the randomization either with Pradaxa® (150 mg bid) or Marcumar® (INR 2-3) for at least three weeks. Thrombus resolution will be determined by transesophageal echocardiography (TEE) 3 weeks after start of treatment and subsequently at week 4 and 6 if necessary, i.e. LAA thrombus has not yet resolved. The study is terminated for each patient with the resolution of the LAA thrombus or after 6 weeks of study treatment.
Phenprocoumon
After inclusion of the patients with LAA thrombus, they are treated according to the randomization either with Pradaxa® (150 mg bid) or Marcumar® (INR 2-3) for at least three weeks. Thrombus resolution will be determined by transesophageal echocardiography (TEE) 3 weeks after start of treatment and subsequently at week 4 and 6 if necessary, i.e. LAA thrombus has not yet resolved. The study is terminated for each patient with the resolution of the LAA thrombus or after 6 weeks of study treatment.
Charité Universitätsmedizin Berlin, Berlin
Städtisches Klinikum Karlsruhe, Karlsruhe
Klinikum Coburg GmbH, Coburg
University Heart Center; Department of Cardiology and Angiology II, Bad Krozingen
Vivantes Clinical Center Am Urban; General Internal Medicine and conservative intensive care, Berlin
University Heart Center; Department of Cardiology, Cologne
University Heart Center; Department of Invasive Electrophysiology, Dresden
University Heart Center; Department of Cardiology, Electrophysiology, Hamburg
Hannover Medical School; Department of Cardiology and Angiology, Hanover
Universitätsmedizin Leipzig, Leipzig
University Hospital Mainz, II. Medical Clinic, Dept. of Electrophysiology, Mainz
University Medical Center, Münster
St. Vincenz-Hospital GmbH, Paderborn
Rostock University Hospital; Rhythmology and Clinical Electrophysiology, Rostock
Collaborators (1)
Boehringer Ingelheim
INDUSTRY
Atrial Fibrillation Network
OTHER
Johannes Gutenberg University Mainz
OTHER