Dapagliflozin Effects on Epicardial Fat

PHASE4CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

September 30, 2015

Primary Completion Date

September 10, 2020

Study Completion Date

September 10, 2020

Conditions
Type 2 Diabetes
Interventions
DRUG

Dapagliflozin

5 mg taken orally once daily. After 2 weeks, if there are no safety issues as per treating physician discretion, the dose can be titrated up to 10 mg orally taken once daily.

DRUG

Metformin

500 mg taken orally twice daily to a maximum of 1000 mg twice daily to achieve a fasting glucose between 80-140 md/dL

DRUG

Placebo

Placebo pill taken once daily to mimic Dapagliflozin

Trial Locations (1)

33136

University of Miami, Miami

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

University of Miami

OTHER