Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of BI 653048 BS H3PO4 Capsule Assessing Endotoxin-induced Inflammatory Response in Healthy Male Subjects

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

March 31, 2010

Primary Completion Date

May 31, 2010

Conditions

Healthy

Interventions

DRUG

BI 653048 BS

DRUG

Prednisolone low

DRUG

Prednisolone high

DRUG

Placebo

DRUG

sodium chloride infusion

DRUG

endotoxin escherichia coli (E. coli) lipopolysaccharide (LPS)