The Effect of Topical Treatment With Combigan Compared to Timolol and Brimonidine on Pupil Diameter

PHASE2UnknownINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

October 31, 2015

Primary Completion Date

August 31, 2016

Study Completion Date

December 31, 2016

Conditions
Healthy
Interventions
DRUG

Combigan (Combination of Brimonidine and Timolol)

On the first exam the subject will receive Combigan (Combination of Brimonidine and Timolol) eye drop to the right eye and a Brimonidine drop to the left eye. The effect on pupil size before and 30 minutes, 60 minutes, 240 minutes, and 300 minutes after instillation of eyedrops. On the second exam the subject will receive Timolol (0.5%) eye drop to the right eye and a Brimonidine drop to the left eye. The effect on pupil size before and 30 minutes, 60 minutes, 240 minutes, and 300 minutes after instillation of eyedrops.

DRUG

Timolol

0.5% eye drop

Trial Locations (1)

34362

Carmel Medical Center, Haifa

Sponsors
All Listed Sponsors
lead

Carmel Medical Center

OTHER