Immunoregulatory T Lymphocytes Subtypes and Haematopoietic Stem Cell Transplantation (HSCT)

"1. Adult recipient:~ * collected 20 ml pre-transplant~ * collected 30 ml for adults on day 20 post-transplant at engraftment for cell phenotype,~ * collected 30 ml on days 30, 60, 90, 180, 360 days post-HSCT for cell phenotyping at all time points, functional INKT at day 60 or 90 depending on the number of cells collected and anti-viral ELISPOT studies on days 180 and 360~2. Children recipients~ * collected residual blood pre-transplant~ * collected residual blood on day 20 post-transplant at engraftment for cell phenotype,~ * collected residual blood on days 20, 30, 90, 180 and 360 post-HSCT"

"1. Adult donors :~ * collected 20 ml of blood, (if possible before granulocyte colony-stimulating factor (GCSF) administration)~ * collected 1 ml of the stem cell graft for adult recipient or 2 ml of bone marrow for children recipients These samples will be collected at the same time of those needed for transplant.~2. Children donors samples~ * collected residual blood~ * 2ml of bone marrow (bottom of tube)"