19
Participants
Start Date
March 11, 2016
Primary Completion Date
January 5, 2024
Study Completion Date
July 5, 2024
17B-estradiol
Anti-estrogen
Letrozole
Aromatase inhibitors work by blocking estrogen receptors; they stop a key enzyme (called aromatase) from changing other hormones into estrogen. This lowers estrogen levels in the body, taking away the fuel that estrogen receptor-positive breast cancers need to grow.
Anastrozole
Aromatase inhibitors work differently from tamoxifen and raloxifene. Instead of blocking the estrogen receptors, they stop a key enzyme (called aromatase) from changing other hormones into estrogen. This lowers estrogen levels in the body, taking away the fuel that estrogen receptor-positive breast cancers need to grow.
Exemestane
Aromatase inhibitors work differently from tamoxifen and raloxifene. Instead of blocking the estrogen receptors, they stop a key enzyme (called aromatase) from changing other hormones into estrogen. This lowers estrogen levels in the body, taking away the fuel that estrogen receptor-positive breast cancers need to grow.
Mayo Clinic Cancer Center, Rochester
Baystate Medical Center, Springfield
Dartmouth Hitchcock Medical Center, Lebanon
Dartmouth-Hitchcock Medical Center
OTHER