NCT02188459View on ClinicalTrials.gov

Placebo-controlled Trial of Bupropion for Smoking Cessation in Pregnant Women

PHASE2CompletedINTERVENTIONAL

Enrollment

129

Participants

Timeline

Start Date

October 30, 2014

Primary Completion Date

January 22, 2020

Study Completion Date

January 22, 2020

Conditions

SmokingNicotine Dependence

Interventions

DRUG

Bupropion

A total of 360 participants will be randomly assigned to one of two treatment conditions: Bupropion 300 mg/day (n = 180) or placebo (n = 180). We will use small-block randomization by site (Penn). A PHQ-9 score of 10 or greater will be used to identify major depression and stratify the randomization on it. Study site (Penn) will be the second of the two stratification variables.

Trial Locations (3)

19104

University of Pennsylvania, Philadelphia

19107

Thomas Jefferson University, Philadelphia

19713

Christiana Care Health System, Newark

All Listed Sponsors

lead

Henry Kranzler

OTHER

NCT02188459 - Placebo-controlled Trial of Bupropion for Smoking Cessation in Pregnant Women | Biotech Hunter | Biotech Hunter