20,723
Participants
Start Date
June 15, 2016
Primary Completion Date
October 15, 2022
Study Completion Date
December 29, 2022
Hydrochlorothiazide (HCTZ)
Trial activities following study randomization were considered as usual care. Prescriptions of the allocated drug were managed by the primary care providers and patients would receive the prescribed mediations through the VA outpatient pharmacy services.
Chlorthalidone (CTD)
Trial activities following study randomization were considered as usual care. Prescriptions of the allocated drug were managed by the primary care providers and patients would receive the prescribed mediations through the VA outpatient pharmacy services.
Manhattan Campus of the VA NY Harbor Healthcare System, New York, NY, New York
Albany VA Medical Center Samuel S. Stratton, Albany, NY, Albany
Syracuse VA Medical Center, Syracuse, NY, Syracuse
VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh
Wilkes-Barre VA Medical Center, Wilkes-Barre, PA, Wilkes-Barre
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia
Coatesville VA Medical Center, Coatesville, PA, Coatesville
Wilmington VA Medical Center, Wilmington, DE, Wilmington
Washington DC VA Medical Center, Washington, DC, Washington D.C.
Rehabilitation R&D Service, Baltimore, MD, Baltimore
Hampton VA Medical Center, Hampton, VA, Hampton
Huntington VA Medical Center, Huntington, WV, Huntington
Durham VA Medical Center, Durham, NC, Durham
Wm. Jennings Bryan Dorn VA Medical Center, Columbia, SC, Columbia
North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville
Bay Pines VA Healthcare System, Pay Pines, FL, Bay Pines
Birmingham VA Medical Center, Birmingham, AL, Birmingham
Memphis VA Medical Center, Memphis, TN, Memphis
VA Gulf Coast Veterans Health Care System, Biloxi, MS, Biloxi
Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
Cincinnati VA Medical Center, Cincinnati, OH, Cincinnati
Dayton VA Medical Center, Dayton, OH, Dayton
Aleda E. Lutz VA Medical Center, Saginaw, MI, Saginaw
William S. Middleton Memorial Veterans Hospital, Madison, WI, Madison
Tomah VA Medical Center, Tomah, WI, Tomah
Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis
St. Cloud VA Health Care System, St. Cloud, MN, Saint Cloud
VA Black Hills Health Care System Fort Meade Campus, Fort Meade, SD, Sturgis
Fargo VA Healthcare System, Fargo, ND, Fargo
Captain James A. Lovell Federal Health Care Center, North Chicago, IL, North Chicago
VA Illiana Health Care System, Danville, IL, Danville
St. Louis VA Medical Center John Cochran Division, St. Louis, MO, St Louis
Kansas City VA Medical Center, Kansas City, MO, Kansas City
Veterans Health Care System of the Ozarks, Fayetteville, AR, Fayetteville
Jackson C. Montgomery VA Medical Center, Muskogee, OK, Muskogee
VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX, Dallas
Michael E. DeBakey VA Medical Center, Houston, TX, Houston
South Texas Health Care System, San Antonio, TX, San Antonio
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora
Grand Junction VA Medical Center, Grand Junction, CO, Grand Junction
Sheridan VA Medical Center, Sheridan, WY, Sheridan
Boise VA Medical Center, Boise, ID, Boise
VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles
VA Long Beach Healthcare System, Long Beach, CA, Long Beach
VA Central California Health Care System, Fresno, CA, Fresno
VA Portland Health Care System, Portland, OR, Portland
VA Roseburg Healthcare System, Roseburg, OR, Roseburg
VA Southern Oregon Rehabilitation Center and Clinics, White City, OR, White City
Alaska VA Healthcare System, Anchorage, AK, Anchorage
Central Arkansas VHS John L. McClellan Memorial Veterans Hospital, Little Rock, AR, Little Rock
VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven
VA Pacific Islands Health Care System, Honolulu, HI, Honolulu
Edward Hines Jr. VA Hospital, Hines, IL, Hines
Richard L. Roudebush VA Medical Center, Indianapolis, IN, Indianapolis
VA Central Iowa Health Care System, Des Moines, IA, Des Moines
Iowa City VA Health Care System, Iowa City, IA, Iowa City
Maine VA Medical Center, Augusta, ME, Togus
Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA, Bedford
VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis
Omaha VA Nebraska-Western Iowa Health Care System, Omaha, NE, Omaha
Manchester VA Medical Center, Manchester, NH, Manchester
New Mexico VA Health Care System, Albuquerque, NM, Albuquerque
Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Memphis VA Medical Center, Memphis, TN, Memphis
Tennessee Valley Healthcare System Nashville Campus, Nashville, TN, Nashville
White River Junction VA Medical Center, White River Junction, VT, White River Junction
Clement J. Zablocki VA Medical Center, Milwaukee, WI, Milwaukee
VA Caribbean Healthcare System, San Juan, PR, San Juan
VA Office of Research and Development
FED