Multiple Dose Comparison of Tiotropium Inhalation Capsules, Salmeterol Inhalation Aerosol and Placebo in Patients With Chronic Obstructive Pulmonary Disease (COPD)

PHASE3CompletedINTERVENTIONAL

Enrollment

623

Participants

Timeline

Start Date

February 28, 1999

Primary Completion Date

May 31, 2000

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

DRUG

Tiotropium (Ba679 BR)

One capsule once daily by oral inhalation

DRUG

Salmeterol

Inhalation aerosol twice daily

DRUG

Placebo (for Tiotropium )

Placebo for Tiotropium delivered by inhalation capsule

DRUG

Placebo (for Salmeterol)

Placebo for Salmeterol delivered by inhalation aerosol