NCT02161783View on ClinicalTrials.gov

Treatment of Graft Failure After Hematopoietic Stem Cell Transplantation

RecruitingOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

October 6, 2014

Primary Completion Date

January 24, 2032

Study Completion Date

January 30, 2032

Conditions
Primary Graft FailureSecondary Graft Failure
Interventions
DRUG

Fludarabine

Fludarabine 30 mg/m2 IV over 1 hour given on days -6 through -2 of transplant.

DRUG

Cyclophosphamide

Cyclophosphamide 14.5 mg/kg IV over 1-2 hours given on days -6 and -5 from transplant. And Cyclophosphamide 50 mg/kg IV over 2 hours given on days +3 and +4 from transplant.

RADIATION

Total Body Irradiation

TBI 200cGy in a single fraction on day -1 from transplant.

BIOLOGICAL

Hematopoietic stem cell infusion

Hematopoietic stem cell infusion given on day 0.

Trial Locations (1)

55455

RECRUITING

University of Minnesota Medical Center, Fairview, Minneapolis

All Listed Sponsors
lead

Masonic Cancer Center, University of Minnesota

OTHER