Pyridorin in Diabetic Nephropathy

PHASE3TerminatedINTERVENTIONAL
Enrollment

328

Participants

Timeline

Start Date

June 30, 2014

Primary Completion Date

December 31, 2017

Study Completion Date

March 31, 2018

Conditions
Diabetic NephropathyDiabetic Kidney Disease
Interventions
DRUG

Pyridorin

300 mg BID (twice daily, every 12 hours), oral capsule taken until end stage renal disease or death occurs, or the study is terminated by the sponsor.

DRUG

Placebo

Placebo excipients without the active drug, oral capsule taken BID (twice daily, every 12 hours), until end stage renal disease or death occurs, or the study is terminated by the sponsor.

Trial Locations (137)

1032

CSG Investigational Site (#509), Budapest

1036

CSG Investigational Site (#513), Budapest

1096

CSG Investigational Site (#505), Budapest

2011

CSG Investigational Site (#207), Footscray

2050

CSG Investigational Site (#205), Camperdown

2065

CSG Investigational Site (#208), St Leonards

2170

CSG Investigational Site (#206), Liverpool

2250

CSG Investigational Site (#201), Gosford

3000

CSG Investigational Site (#502), Hatvan

3050

CSG Investigational Site (#209), Parkville

3073

CSG Investigational Site (#200), Reservoir

3121

CSG Investigational Site (#202), Richmond

3800

CSG Investigational Site (#500), Szikszó

4032

CSG Investigational Site (#507), Debrecen

4600

CSG Investigational Site (#510), Kisvárda

5000

CSG Investigative Site (#204), Adelaide

5701

CSG Investigational Site (#508), Gyula

7400

CSG Investigational Site (#504), Kaposvár

7623

CSG Investigational Site (#506), Pécs

8000

CSG Investigational Site (#514), Székesfehérvár

8230

CSG Investigational Site (#501), Balatonfüred

8900

CSG Investigational Site (#503), Zalaegerszeg

10249

CSG Investigative Site (#702), Berlin

10994

CSG Investigational Site (#154), West Nyack

11768

CSG Investigational Site (#136), Northport

13100

CSG Investigational Site (#308), Safed

14215

CSG Investigational Site (#128), Buffalo

15208

CSG Investigational Site (#315), Poria – Neve Oved

15240

CSG Investigational Site (#149), Pittsburgh

17007

CSG Investigational Site (#600), Girona

19104

CSG Investigational Site (#101), Philadelphia

20770

CSG Investigational Site (#147), Greenbelt

22030

CSG Investigational Site (#137), Fairfax

22033

CSG Investigational Site (#103), Fairfax

22100

CSG Investigational Site (#302), Nahariya

22908

CSG Investigational Site (#129), Charlottesville

23249

CSG Investigational Site (#144), Richmond

23666

CSG Investigational Site (#104), Hampton

25198

CSG Investigational Site (# 607), Lleida

27157

CSG Investigational Site (#127), Winston-Salem

27710

CSG Investigational Site (#125), Durham

28207

CSG Investigational Site (#116), Charlotte

28562

CSG Investigational Site (#155), New Bern

28702

CSG Investigational Site (#601), San Sebastián de los Reyes

28801

CSG Investigational Site (#108), Asheville

31096

CSG Investigational Site (#300), Haifa

31901

CSG Investigational Site (#156), Columbus

34295

CSG Investigational Site (#806), Montpellier

35294

CSG Investigational Site (#157), Birmingham

37205

CSG Investigational Site (#105), Nashville

37408

CSG Investigational Site (#131), Chattanooga

38043

CSG Investigational Site (#801), Grenoble

43210

CSG Investigational Site (#106), Columbus

44106

CSG Investigational Site (#151), Cleveland

44130

CSG Investigational Site (#148), Parma Heights

44195

CSG Investigational Site (#123), Cleveland

44281

CSG Investigational Site (#309), Kfar Saba

45267

CSG Investigational Site (#124), Cincinnati

46017

CSG Investigational Site (#602), Valencia

46360

CSG Investigational Site (#102), Michigan City

48202

CSG Investigational Site (#111), Detroit

48341

CSG Investigational Site (#134), Pontiac

49100

CSG Investigational Site (#312), Petah Tikva

52621

CSG Investigational Site (#310), Tel Hasomer

53295

CSG Investigational Site (#122), Milwaukee

55116

CSG Investigational Site (#708), Mainz

58100

CSG Investigational Site (#304), Holon

59322

CSG Investigational Site (#805), Valenciennes

60607

CSG Investigational Site (#113), Chicago

62039

CSG Investigational Site (#305), Tel Aviv

62321

CSG Investigational Site (#800), Boulogne-sur-Mer

63739

CSG Investigational Site (#709), Aschaffenburg

64111

CSG Investigational Site (#162), Kansas City

64128

CSG Investigational Site (#152), Kansas City

68024

CSG Investigational Site (#803), Colmar

69115

CSG Investigational Site (#703), Heidelberg

69310

CSG Investigational Site (#804), Rhone

70112

CSG Investigational Site (#115), New Orleans

70300

CSG Investigational Site (#301), Ẕerifin

75390

CSG Investigational Site (#119), Dallas

75650

CSG Investigational Site (#311), Rishon LeZiyyon

75877

CSG Investigational Site (#802), Paris

77004

CSG Investigational Site (#139), Houston

77076

CSG Investigational Site (#133), Houston

78278

CSG Investigational Site (#307), Ashkelon

79707

CSG Investigational Site (#109), Midland

80002

CSG Investigational Site (#153), Arvada

80031

CSG Investigational Site (#120), Westminster

80045

CSG Investigational Site (#118), Aurora

81675

CSG Investigational Site (#700), München

84101

CSG Investigational Site (#313), Beersheba

84112

CSG Investigational Site (#132), Salt Lake City

85012

CSG Investigational Site (#130), Phoenix

85054

CSG Investigational Site (#150), Phoenix

85745

CSG Investigational Site (#142), Tucson

86301

CSG Investigational Site (#145), Prescott

89115

CSG Investigational Site (#141), Las Vegas

90048

CSG Investigational Site (#160), Los Angeles

91120

CSG Investigational Site (#306), Jerusalem

92505

CSG Investigational Site (#143), Riverside

93106

CSG Investigational Site (#314), Jerusalem

95661

CSG Investigational Site (#159), Roseville

99204

CSG Investigational Site (#121), Spokane

06708

CSG Investigational Site (#158), Waterbury

02111

CSG Investigational Site (#117), Boston

01107

CSG Investigational Site (#114), Springfield

02903

CSG Investigational Site (#146), Providence

05401

CSG Investigational Site (#107), Burlington

Unknown

CSG Investigational Site (#757), Plovdiv

CSG Investigational Site (# 750), Sofia

CSG Investigational Site (# 755), Sofia

CSG Investigational Site (# 756), Sofia

CSG Investigational Site (#751), Sofia

CSG Investigational Site (#752), Sofia

CSG Investigational Site (#753), Sofia

CSG Investigational Site (#754), Stara Zagora

CSG Investigational Site (#400), Hong Kong

CSG Investigational Site (#402), Kwai Chung

CSG Investigational Site (#401), Shatin

CSG Investigational Site (#303), Tel Aviv

CSG Investigational Site (# 850), Phoenix

CSG Investigational Site (#651), Bydgoszcz

CSG Investigational Site (#655), Chojnice

CSG Investigational Site (#653), Kielce

CSG Investigational Site (#657), Nowy Sącz

CSG Investigational Site (#652), Poznan

CSG Investigational Site (#656), Poznan

04910

CSG Investigational Site (#706), Elsterwerda

04916

CSG Investigational Site (#707), Herzberg

02977

CSG Investigational Site (#701), Hoyerswerda

00935

CSG Investigational Site (#112), Rio Piedras

00918

CSG Investigational Site (#110), San Juan

00949

CSG Investigational Site (#135), Toa Baja

08003

CSG Investigational Site (#605), Barcelona

08022

CSG Investigational Site (#606), Barcelona

08025

CSG Investigational Site (#603), Barcelona

08907

CSG Investigational Site (#604), Barcelona

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Collaborative Study Group (CSG)

NETWORK

collaborator

Medpace, Inc.

INDUSTRY

lead

NephroGenex, Inc.

INDUSTRY

NCT02156843 - Pyridorin in Diabetic Nephropathy | Biotech Hunter | Biotech Hunter