Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases

PHASE2CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

August 3, 2016

Primary Completion Date

June 30, 2018

Study Completion Date

February 16, 2021

Conditions
Brain Metastases
Interventions
RADIATION

Hippocampal sparing whole brain radiotherapy

30 Gy in 10 fractions hippocampal sparing whole brain radiotherapy will be administered by Helical Tomotherapy, IMRT, or VMAT

RADIATION

Conventional whole brain radiotherapy

30 Gy in 10 fractions conventional whole brain radiotherapy will be administered

Trial Locations (7)

N4 3SL

University Hospitals Birmingham NHS Foundation Trust, Birmingham

Unknown

Addenbrooke's Hospital, Cambridge

Royal Surrey County Hospital, Guildford

Nottingham University Hospitals, Nottingham

Barking, Havering and Redbridge University Hospitals Nhs Trust, Romford

W6 8RF

Charing Cross Hospital, London

M20 4BX

The Christie NHS Foundation Trust, Manchester

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Cancer Research UK

OTHER

collaborator

The Brain Tumour Charity

OTHER

lead

University College, London

OTHER