OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP

PHASE4UnknownINTERVENTIONAL
Enrollment

486

Participants

Timeline

Start Date

December 31, 2011

Primary Completion Date

May 31, 2020

Study Completion Date

June 30, 2022

Conditions
Bronchopulmonary Dysplasia
Interventions
DEVICE

Minimally invasive surfactant therapy

Active Comparator

OTHER

Continuation on CPAP

Sham Comparator

Trial Locations (16)

1142

Auckland City Hospital, Auckland

1640

Middlemore Hospital, Auckland

3052

Royal Womens Hospital, Melbourne

3084

Mercy Hospital for Women, Melbourne

3168

Monash Medical Centre, Melbourne

7000

Royal Hobart Hospital, Hobart

13100

Ziv Medical Center, Safed

16120

Uludag University Hospital, Görükle

26506

West Virginia University Hospital, Morgantown

31048

Bnai Zion Medical Center, Haifa

60201

NorthShore Health University HealthSystem Evanston Hospital, Evanston

96826

Kapi'olani Medical Center for Women and Children, Honolulu

06520-8081

Yale-New Haven Children's Hospital, New Haven

08103

Cooper University Hospital, Camden

SI-1525

University Medical Center, Ljubljana, Zaloska

06230

Zekai Tahir Burak Hospital, Ankara

All Listed Sponsors
collaborator

Royal Hobart Hospital

OTHER_GOV

collaborator

Royal Women's Hospital, Melbourne, Australia

UNKNOWN

collaborator

Endeavor Health

OTHER

collaborator

Monash Medical Centre

OTHER

collaborator

Mercy Hospital for Women, Australia

OTHER

collaborator

Auckland City Hospital

OTHER_GOV

collaborator

Middlemore Hospital, New Zealand

OTHER

collaborator

Zekai Tahir Burak Women's Health Research and Education Hospital

OTHER

collaborator

Kapiolani Medical Center For Women & Children

OTHER

collaborator

The Cooper Health System

OTHER

collaborator

Yale University

OTHER

collaborator

West Virginia University Hospital

UNKNOWN

collaborator

Uludag University Hospital

UNKNOWN

collaborator

Ziv Medical Center

OTHER

collaborator

Bnai Zion Medical Center

OTHER_GOV

collaborator

University Medical Centre Ljubljana

OTHER

collaborator

Dunedin Hospital

OTHER

collaborator

Kanuni Sultan Suleyman Training and Research Hospital

OTHER

collaborator

University Medical Center Groningen

OTHER

collaborator

University of Southern California

OTHER

lead

Menzies Institute for Medical Research

OTHER