37
Participants
Start Date
July 31, 2008
Primary Completion Date
August 31, 2010
Study Completion Date
August 31, 2010
Double dose of Salmeterol + Fluticasone Propionate
Self-management education on the use of a self-administered prescription for exacerbation.
Patients will be instructed to start treatment within 48 hours of experiencing an acute exacerbation of COPD and/or after starting their self-administered prescription.
Self-administered prescription
"An Acute Exacerbation of COPD (AECOPD) is defined as a sustained worsening of dyspnea, cough or sputum production leading to an increase in the use of maintenance medication and/or supplementation with additional medication. In addition, exacerbations should be defined as either purulent or non-purulent.~Standing prescriptions for exacerbation:~1\) Purulent exacerbation - Antibiotic: Avelox 400 mg daily for 5 days. 2a) Mild to moderate exacerbation - Combination therapy (SFP - Advair) to be increased as follows: If regular treatment is Advair 250/50 BID then dose should be increased to Advair 500/100 BID for 10 days; if regular treatment is Advair 500/50 BID then increase to Advair 1000/100 BID for 10 days.~2b) Severe exacerbation - Prednisone (oral): 40 mg once daily for 7-10 days"
Montreal Chest Institute, Montreal
Collaborators (1)
GlaxoSmithKline
INDUSTRY
McGill University Health Centre/Research Institute of the McGill University Health Centre
OTHER