NCT02135263View on ClinicalTrials.gov

Metabolism of Methylphenidate and Enalapril Based on CES1 Genotype

PHASE4CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

April 30, 2012

Primary Completion Date

May 31, 2014

Study Completion Date

May 31, 2014

Conditions
Carboxylesterase 1 (CES1) GenotypeCES1 Activity
Interventions
DRUG

Methylphenidate

10 mg as a single dose followed by blood samples for the next 33 hours

DRUG

Enalapril

10 mg as a single dose followed by blood samples for the next 72 hours

Trial Locations (1)

2400

Department of Clinical Pharmacology, Bispebjerg University Hospital, Copenhagen

Sponsors

Collaborators (1)

Duke University
All Listed Sponsors
collaborator

The Ministry of Science, Technology and Innovation, Denmark

OTHER_GOV

collaborator

Mental Health Centre Sct. Hans (Denmark)

UNKNOWN

collaborator

University of Copenhagen

OTHER

collaborator

The Leiden Academic Center for Drug Research (LACDR)

UNKNOWN

collaborator

Duke University

OTHER

lead

Bispebjerg Hospital

OTHER

NCT02135263 - Metabolism of Methylphenidate and Enalapril Based on CES1 Genotype | Biotech Hunter | Biotech Hunter