A Study of the Safety and Efficacy of Pembrolizumab (MK-3475) in Combination With Trametinib and Dabrafenib in Participants With Advanced Melanoma (MK-3475-022/KEYNOTE-022)

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

184

Participants

Timeline

Start Date

May 29, 2014

Primary Completion Date

July 14, 2021

Study Completion Date

July 14, 2021

Conditions
MelanomaSolid Tumors
Interventions
BIOLOGICAL

Pembrolizumab

IV infusion

DRUG

Dabrafenib

oral capsule

DRUG

Trametinib

oral tablet

DRUG

Placebo

IV infusion

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis Pharmaceuticals

INDUSTRY

lead

Merck Sharp & Dohme LLC

INDUSTRY