Adenosine-induced Myocardial Blood Flow in Peripheral Artery Disease Patients

PHASE4WithdrawnINTERVENTIONAL
0
Timeline

Start Date

December 31, 2014

Primary Completion Date

February 29, 2016

Study Completion Date

February 29, 2016

Conditions
Peripheral Artery DiseaseVascular DiseaseArterial Occlusion DiseaseIntermittent ClaudicationAnkle Brachial Index (0.9 or Less)
Interventions
DRUG

Ticagrelor

Day 1: Loading dose of ticagrelor 180mg (two 90mg tablets) followed by 90mg dose at 12 hours after loading dose. Subject continues to take ticagrelor 90mg twice a day (morning and evening) for 7 days until next visit (Day 7).

DRUG

clopidogrel

Day 1: Clopidogrel 75mg oral tablet. Subjects will continue to take clopidogrel 75mg once a day for 7 days until next visit (Day 7/Visit 3). Note: no loading dose is given for the clopidogrel as those subjects are already on chronic dosing.

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AstraZeneca

INDUSTRY