Concomitant Milrinone and Esmolol Treatment in Patients with Acute Myocardial Infarction

PHASE2CompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

May 31, 2015

Primary Completion Date

March 31, 2023

Study Completion Date

December 31, 2024

Conditions
Myocardial Reperfusion Injury
Interventions
DRUG

Milrinone

"Approximately 5 minutes before stent deployment, the patients in the milrinone+esmolol group start to receive continuous intravenous drug infusion for 10 minutes. Milrinone and esmolol (each in 10 ml volume) will be placed in two separate syringes being connected to their respective venous catheters.~Dosage of study drugs: Syringe #1 Milrinone 5 ug/kg/min Syringe #2 Esmolol 10 ug/kg/min"

DRUG

Esmolol

"Approximately 5 minutes before stent deployment, the patients in the milrinone+esmolol group start to receive continuous intravenous drug infusion for 10 minutes. Milrinone and esmolol (each in 10 ml volume) will be placed in two separate syringes being connected to their respective venous catheters.~Dosage of study drugs: Syringe #1 Milrinone 5 ug/kg/min Syringe #2 Esmolol 10 ug/kg/min"

DRUG

Saline Infusion

Approximately 5 minutes before stent deployment, the patients in the placebo group start to receive continuous intravenous saline infusion for 10 minutes. Two syringes containing saline (10 ml volume in each) will be connected to two separate venous catheters during the infusion

Trial Locations (1)

119077

National University Hospital, Singapore, Singapore

All Listed Sponsors
collaborator

National University Hospital of Singapore

UNKNOWN

lead

Shantou University Medical College

OTHER

NCT02098629 - Concomitant Milrinone and Esmolol Treatment in Patients with Acute Myocardial Infarction | Biotech Hunter | Biotech Hunter