269
Participants
Start Date
April 1, 2014
Primary Completion Date
March 30, 2018
Study Completion Date
December 30, 2025
Ventral (Front) decompression with Fusion
Ventral decompression and fusion will be performed using a multi-level discectomy (including partial or single level corpectomy) with fusion and plating. Allograft will be used at each disc space and all compressive osteophytes will be removed using the operating microscope. Fixation will be performed with rigid, semi-constrained, or dynamic titanium plates to optimize fusion and minimize complications.
Dorsal (Back) Decompression with Fusion
Dorsal decompression and fusion will be performed using midline cervical laminectomy with the application of lateral mass screws and rods for rigid fixation. All surgeons will use local bone and allograft as needed to perform a lateral mass fusion, which typically will include one level rostral to the levels decompressed.
Dorsal (back) Laminoplasty
Laminoplasty will be performed using an open-door approach with the application of plates and screws at each treated level. Ceramic or allograft laminar spacers (surgeon's choice) can be used with plates and screws to expand the canal diameter.
Hospital for Special Surgery, New York
Columbia, New York
University of Pittsburgh Medical Center, Pittsburgh
Thomas Jefferson University Hospital, Philadelphia
Emory, Atlanta
Cleveland Clinic Foundation, Cleveland
MetroHealth, Cleveland
Medical College of Wisconsin, Milwaukee
University of Wisconsin, Madison
Washington University School of Medicine- St. Louis, St Louis
University of Kansas Medical Center, Kansas City
University of Utah Health Sciences, Salt Lake City
University of California- San Francisco, San Francisco
Lahey Hospital and Medical Center, Burlington
Rutgers-New Jersey Medical School, Newark
University Health Network-University of Toronto, Toronto
Lead Sponsor
Patient-Centered Outcomes Research Institute
OTHER
Lahey Clinic
OTHER