63
Participants
Start Date
February 28, 2015
Primary Completion Date
October 6, 2022
Study Completion Date
October 6, 2022
Pamidronate
Subjects randomized to pamidronate treatment will receive infusions, 1 mg/kg (to a max dose of 60mg) over 4 hours, every 3 months at approximately 100 days, 180 days, and 270 days after HCT.
Calcium and vitamin D
All subjects will receive a standard recommended dose of 600 IU/day of vitamin D. Subjects who do not meet the RDA will receive additional calcium supplementation.
University of Minnesota Amplatz Children's Hospital, Minneapolis
Seattle Children's Hospital, Seattle
Masonic Cancer Center, University of Minnesota
OTHER